Dermatologist - Savannah
639 Stephenson Ave
Savannah, GA 31405
912-354-7124

Photodynamic Therapy

BLU-U® Light

Photodynamic Therapy: State-of-the-Art Treatment for Acne and Precancers
Photodynamic therapy is one of the most exciting advancements in dermatology in the last 10 years. It is a promising new treatment for precancers and acne involving three key components: a photosensitizer, light, and tissue oxygen. It is used to treat precancers and actinic damage over the entire face and scalp. A solution called levulinic acid is applied to the area and allowed to sit for one hour. Then, a blue light is used to activate the solution which then "attacks" the precancerous cells of the face. The result is a sunburn-like reaction lasting 4-7 days. Not only are precancerous lesions treated leading to a decreased chance of skin cancer, but also the entire face is rejuvenated, smoother and less photodamaged.

What happens during the procedure?
First, your skin will be thoroughly cleansed before the photosensitizing drug is applied. This scrubbing will help the skin absorb the drug more readily. Then a clear solution called aminolevulinic acid will be applied to the entire surface of the treated skin.

The drug will need time to penetrate the skin. The recommend period of time may from one hour to several hours.  The area is then treated with a blue light for approximatelly 17 minutes.

During the procedure, you may feel a burning sensation on certain parts of your skin, which can be alleviated by cold air or fans. Afterward, it will be extremely important to protect your skin from light for 48 hours, as it will be very light-sensitive. Avoid going out in the sun during this time if you can, but if you can’t avoid being outside, wear long sleeves and pants, a brimmed hat and a scarf, and thick zinc-oxide-based sunblock.
 

Are there any complications from PDT?
For the first few days after treatment, you may experience skin redness, irritation, and peeling, as well as mild discomfort that feels like a sunburn. If these symptoms persist or seem severe, contact your doctor. 

In addition to the mild side effects listed above, PDT can also lead to skin crusting or prolonged irritation and peeling. More serious reactions can occur in people treated for a large number of pre-cancerous lesion, because their skin is absorbing more of the drug. Complications can also arise in people who fail to protect their skin from the sun after treatment—it’s important to remember that the sun can penetrate the skin even on cloudy days or inside a car.

Fortunately, these complications usually go away within a week or two and don’t interfere with the treatment’s results.

OTHER USES FOR PDT
Blue-U® therapy or PDT can be used off label to treat acne and rosacea.  Usually several treatments are needed.  This can be used in combination with other treatments such as topicals and oral medications.